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Rapid population growth, natural and man-made factors (COVID-19 and the lack of a social safety net) have led to an increase in the demand for food, which calls for significant improvements to the food system worldwide to supply food more efficiently with the same or fewer resources. Potatoes have great potential to contribute to food security and incomes for rural smallholder farmers, as well as provide nutritious, affordable food for urban consumers. The availability of disease-free and certified seed potatoes of better-performing varieties remains limited. The use of tissue culture to provide a disease-free seed potato is therefore crucial to ensuring food security. A key goal of this paper is to summarize the work done on various aspects of seed potato multiplication, and how it can improve the food security of smallholder farmers. The systematic review method was applied to summarize how tissue culture application can produce excess disease-free seed potatoes to improve food availability for marginal farmers. The most effective way for farmers in developing countries or areas prone to natural or man-made disasters to increase their incomes and improve nutrition is to use high-quality certified seeds. Tissue cultures are used worldwide to produce pre-basic, virus-free seed potatoes. Early Generation Seed (micro-tubers, cuttings and mini-tuber), multiplication of mother plants and production of apical rooted cutting for seed production for field planting are popular. The activities of diseases-free seed production start at the laboratory and end at the field with seed production for planting. In general, three major steps were used in seed potato multiplication: (1) Tissue culture (to produce disease-free tissue culture plantlets);(2) Production of cuttings (involves two important stages: (i) multiplication of mother plants and (ii) production of apical rooted cutting for planting) for further multiplication and (3) production of seeds for field planting.
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Aim: The contagious disease COVID 19 is a recently out-broken pandemic situation which threatens humankind all over the world. Siddha system of medicine is one of the traditional medical systems of India, which has provided a novel remedy for many epidemics like Dengue, Chicken guinea earlier. On evaluating the literature evidence and considering the mortality and severity of the disease, we have attempted to identify the possible inhibition of viral replication by "Karisalai Chooranam" - a polyherbal Siddha formulation which contains herbs like Karisalai (Wedelia chinensis), Thoodhuvelai (Solanum trilobatum), Musumusukai (Melothria maderaspatana) and Seeragam (Cuminum cyminum). The aim of this study was to identify the bioactive components present in Karisalai chooranam and pin down the components that inhibit COVID 19 protease by In Silico molecular docking analysis. Material and methods: The study was performed for the active compounds present in the herbs (Wedelia chinensis - Benzoic acid, Solanum trilobatum- Disogenin, Melothria maderaspatana- beta-sitosterol, Cuminum cyminum L- Coumaric acid and Limonene) with three potential targets, PDB id: 6LU7 3-chymotrypsin-like protease (3CLpro), PDB id: 6-NUR RNA dependent RNA polymerase and PDB id: 2AJF Angiotensin-converting enzyme II (ACE2) receptor using Autodock Vina. Key findings: The active phytocomponents present in "Karisalai chooranam" was found to inhibit the target 3CL proenzyme and hereby halt the formation of 16 non-structural proteins (nsp1-nsp16) that are highly essential for viral replication and there by prevents viral survival in the host environment. The phytocomponents also inhibited the target RNA dependent RNA polymerase (PDB)-6NUR RdRp which possess versatile action in mediating nonstructural protein (nsp 12) essential for viral replication. A significant binding against the target Angiotensin-converting enzyme II (ACE2) receptors - PDB- 2AJF was found which was recognized as a binding site for novel coronavirus to cause its pathogenesis. Among the five active components present in the herb, the binding ability of Disogenin and beta-sitosterol with COVID19 protease suggests a possible mechanism of protease inhibition and thus preventing viral replication. Significance: The results strongly suggest that phytocomponents of "Karisalai chooranam" may act as a potential therapeutic agent for the management of COVID-19 and related symptoms. Further, the efficacy of the active compounds should be tested in vitro before being recommended as a drug.
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Porcine epidemic diarrhea virus (PEDV) has been affecting the swine industry, especially in suckling pigs in with a high mortality rate. Among all the strategies to overcome PEDV, boosting mucosal immunity in pig intestine via oral administration appears to be more efficient than other routes. However, there are biological obstacles such as acidic environment that could damage biologics, a product from organisms often used for PEDV treatment. The plant-derived 2C10 monoclonal antibody (mAb) from Nicotiana benthamiana produced by transient expression was revealed as one of the potential candidates against PEDV through oral delivery. Herein, we demonstrated the calcium-alginate microencapsulation system to protect the 2C10 mAb from the harsh condition in the stomach and to be released the 2C10 mAb when arriving in the intestine. The pH-responsive encapsulated 2C10 mAb microbeads were constructed from the calcium-alginate system. The microbeads were well-tolerated under the acidic environment of simulated gastric fluid (SGF) and were digested under the alkaline condition of simulated intestinal fluid (SIF). The encapsulated 2C10 mAb in the SPF-treated microbeads exhibited high virus neutralization efficiency in Vero cells when compared to the unencapsulated 2C10 mAb treated by SPF that cannot neutralize the virus. For these reasons, calcium-alginate microencapsulation system is an attractive platform to be considered as a candidate for the next generation of oral vaccine development.
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The importance of food supply throughout the world has once again shown its significance in the COVID-19 pandemic period. A continuous food supply is possible with correct agricultural programming. An effective agricultural product programming can only be possible by obtaining precise agricultural data. However, it is very difficult to gather accurate agricultural production statistics from all over the world and confirm their accuracy. In this study, the compatibility of the production statistics of six important agricultural products (wheat, rice, potato, onion, banana, apple) which had been collected from local sources, and had published as opensource by the Food and Agriculture Organization of the United Nations, with Benford's law was examined for the first time. Data for the last two decades are used to ignore the impact of annual fluctuations. The compatibility of theoretically expected and observed data was tested by Chi-square (X2) and Mean Absolute Deviation (MAD) tests. Although inconsistencies were found in some data by examining the numbers in the first, second, and first two digits, in general, the MAD test results gave a mostly concordant result.
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Coronavirus was detected in Bangladesh first time on March 8, 2020 officially. But Coronavirus Disease (COVID-19), first reported in December 2019 from Wuhan in China, had reached the stage of a pandemic. This study was conducted to know the effects of spices against Covid-19 disease, impact of Covid-19 on agro-economy of spices crop and point out of mitigating of spices problem in Bangladesh. Major production of spices was severely affected, causing raw material shortages to the spice production of Bangladesh. Major for spices crop problem were shortages caused by the migration of the workforce due to lockdown. Continuing operation on the industry floor, in the midst of social distancing, and ensuring safety of the spices production, was also a major issue. Although the entire sectors were hit by the economic disruptions, the small-scale spice producers and processors most severely affected. The novel coronavirus disease (COVID-19) pandemic and the prolonged lockdown have made thousands of farmers, labours and traders feel the pinch of a falling spices yield and sale. Increased production cost of onion, chilli, garlic, ginger, turmeric, coriander and black cumin due to Covid-19 situation over normal situation were 10.33, 9.54, 9.04, 11.46, 9.58, 6.21 and 7.21%, respectively. Market price of onion, chilli, garlic, ginger, turmeric, coriander and black cumin were also increased 5.00, 3.90, 1.39, 3.13, 1.40, 1.25 and 2.67 times, respectively, due to the influence of Covid-19.
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The consumption of spices is growing in India with an increase in purchasing power. It is forecasted that everyone in the country would be consuming one spice or the other with a high per capita consumption. It is estimated that we may have a population of around 1.69 billion people during 2050 and approximately the per capita consumption of turmeric, ginger, black pepper and cardamom is expected to be about 1.6 kg, 1.2 kg, 148 g and 54 g, respectively. This may increase further owing to rapid urbanization which needs spices as natural food preservatives. Hence, the present study was conducted to analyze the growth trend in spices economy of India during the period 1990-91 to 2021-22 with reference to the selected growth indicators such as area, production, domestic market, export and export value. For estimating the acceleration in the growth rates, the paper uses semi-logarithmic specification of a non-linear (quadratic) equation. From the analysis, it is observed that there is a huge scope for output and export of spices. Despite the Covid pandemic, spices export from India has continued its upward trend during 2020-21 and has attained an all-time high of US $ 4.0 billion mark for the first time in the history of spices export. It also implies that there is strong domestic market for spices in India.
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Andhra Pradesh is one of the major tomato producing states in the country. The presents tudy was conducted to identify the adoption pattern of 448 variety of tomato in Ananthapuramu district of Andhra Pradesh which was released by IIHR, Bangalore. The study also includes identification of the major factors for adoption and find out the major attributes of innovation that led to the adoption of 448 variety. An ex-post facto research design was adopted for the study. The study included 40 respondents chosen by purposive sampling method. Data was collected with the help of well-structured interview schedule through telephonic interview due to COVID-19 pandemic. The statistical tools used for analysis are mean, standard deviation, cumulative frequency and percentage analysis. Profile characters of the respondents viz., age, educational status, occupation, farm size, farming experience, annual income, frequency of exposure to agricultural messages, scientific orientation and cropping pattern were studied. Based on the mean and SD values the respondents were classified into adopter categories. The results of the adopter categorization showed that two-fifths (40.00%) of respondents belonged to early majority and only 5.00 percent were innovators. Among the factors affecting adoption of 448 variety of tomato, majority (80.00%) adopted due to their own interest and with the influence of friends and neighbours. Compatibility (95.00%) and observability (82.50%) of the variety played an important role among the attributes of innovation for the adoption of 448 variety of tomato among the respondents.
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This study aims to analyze the AntiCovid effect of Phytocompounds extracted from Native Indian Plant species by computational methods such as Molecular Docking. Through this study keeping the Indian Heritage alive we characterized the ability of these phytochemicals as inhibiting agents of the Main Protease enzyme of this Virus. The lack of any effective treatment and the reoccurrence of cases despite Vaccination necessitates the quick provision of anti-SARS-CoV-2 drugs. Natural substances are getting a lot of attention for SARS-CoV-2 therapy as they have proven antimicrobial activities and are a key source for numerous antiviral drugs. Despite the fact that this virus has several identified target receptors, Main Protease (Mpro) is crucial for viral replication. In this study, 26 phytochemicals from 10 native Indian plant species were studied. Our docking studies demonstrated that compounds Quercetin, Withaferin A, Sominone, and Nimbin were likely to be more favorable than the natural inhibitor N3, with binding energies of-8.42, -9.21, -9.95, and -8.88 kcal/mol, respectively. These four candidate natural compounds were further examined for their bioavailability scores through ADMET analysis to prove the safety of these compounds as well as their drug likeliness. Through the results it was indicated that these natural phytochemicals have a significant potential of inhibiting the SARS-CoV-2 Mpro enzyme and might be utilized to treat SARS-CoV-2 and manage public health, subject to in vitro validation in the future.
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Various kinds of field crops growing on two commercial farms in the Whitehorse area of the southern Yukon Territory were surveyed for diseases in summer 2020 by staff of the Agriculture Branch of the Government of Yukon. They included barley, wheat, canola, beets, broccoli, cabbage, carrots, potatoes and turnips. Fields were visited one or more times during July and August. The incidence and severity of diseases were visually assessed on a crop-by-crop basis and samples were collected for laboratory analysis of the pathogens present, if any. Both infectious and non-infectious diseases were present on most crops. The infectious diseases were caused by various species of plant pathogenic bacteria and fungi that were common on these crops growing in other areas of Canada. INTRODUCTION AND METHODS: The 2020 field crop disease survey is believed to be the first organized study of its kind on agricultural crops in the Territory. In his book, "An Annotated Index of Plant Diseases in Canada . . . ", I.L. Conners lists over 300 records of plant diseases on trees, shrubs, herbs and grasses in the Yukon that were published by individuals who were surveying forests and native vegetation mainly for federal government departments, universities and other agencies (Conners 1967). The objectives of the 2020 survey were: (1) to determine the kinds and levels of diseases on selected Yukon crops, (2) to identify the major pathogen species attacking Yukon crops, and (3) to use the results to plan future surveillance activities aimed at helping producers to improve their current disease management programs. All of the fields included in the 2020 survey were situated on two commercial farms, which were designated as Farm #1 and #2, in the Whitehorse area in the southern Yukon (Fig. 1). The crops surveyed included cereals (barley and wheat), oilseeds (canola) and vegetables (beets, broccoli, cabbage, carrots, potatoes and turnips). Fields were visited one or more times in the mid- to late growing season (July/August) at a time when damage from diseases was most noticeable. Symptoms were visually assessed on a crop-by-crop basis by determining their incidence and severity. Incidence was represented by the percentage of plants, leaves, heads, kernels, etc., damaged in the target crop, while severity was estimated to be the proportion of the leaf, fruit, head, root/canopy area, etc., affected by a specific disease as follows: Proportion of the canopy affected based on a 0-4 rating scale, where: 0 = no disease symptoms, 1 = 1-10% of the crop canopy showing symptoms;2 = 11-25% showing symptoms, 3 = 26- 50% showing symptoms, and 4 = > 50% showing symptoms. Photographs of affected plants were taken and sent to plant pathologists across Western Canada for their opinions on causation. Where possible, representative samples of plants with disease symptoms were packaged and sent to the Alberta Plant Health Lab (APHL) in Edmonton, AB for diagnostic analyses. Background information, such as the general cultural practices and cropping history, was obtained from the producers wherever possible. GPS coordinates were obtained for each field to enable future mapping Cereals: Individual fields of barley (11 ha) and wheat (30 ha) located at Farm #1 were surveyed. The barley was a two-row forage cultivar 'CDC Maverick', while the wheat was an unspecified cultivar of Canada Prairie Spring (CPS) Wheat. Plant samples were taken along a W-shaped transect for a total of five sampling points for the barley field (< 20 ha) and ten sampling points for the wheat field (> 20 ha). The first visit, which occurred on July 30, involved visual inspection and destructive sampling wherein plants were collected and removed from the field for a detailed disease assessment at a lab space in Whitehorse. There, the roots were rinsed off and the plants were examined for disease symptoms. The second visit to these fields, which occurred on August 27, only involved visual examination of the standing crop. Oilseeds: A single 40 ha field of Polish canola (cv. 'Synergy') was examined o
ABSTRACT
Cape gooseberry fruits have positioned in the world market due to their excellent nutritional characteristics, because they are an ideal food that contributes to raising the defenses of the human body and helps it to face diseases such as COVID-19, they are also a natural source of antioxidants and anticancer agents. In order to avoid the physiopathy of cracking in cape gooseberry fruits, these were characterized at harvest time, coming from greenhouse plants irrigated with different applications of water levels and irrigation frequencies, as well as different calcium doses, in a design of randomized complete blocks with 12 treatments. The blocks were the irrigation frequencies (4, 9 and 14 days), while the treatments were the combination of four irrigation coefficients (0.7, 0.9, 1.1 and 1.3 of the evaporation of the tank class A) and three doses of calcium (0, 50 and 100 kg ha-1). The plants were sown in 20 L pots with peat moss substrate. Fruits were harvested at the color stage 5 and 6 of the calyx, from 19 weeks after transplanting. The different water levels and irrigation frequencies did not significantly affect the firmness of the cape gooseberry fruits, but there was a strong tendency that cracked gooseberry fruits are less firm than healthy fruits. As the irrigation coefficient increased, the total soluble solids (TSS) increased while the total titratable acids (TTA) decreased. Irrigation frequency of 14 days generated fruits with higher TSS and pH values. The calcium doses did not affect the calcium concentration in the fruits or the TSS, TTA and pH values. Therefore, it can be concluded that incremented irrigation coefficients (up to 1.3) increase the quality of cape gooseberry fruits.
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Edible vaccines are created from transgenic plants and animals and contain immunostimulant. Edible vaccines, to put it simply, are medications generated from plants or animals. In underdeveloped countries, oral vaccines are less expensive and more widely available. Researchers came up with the idea of edible vaccines, in which edible plant pieces are employed as a vaccine factory. To make edible vaccinations, scientists put desired genes into plants and then force the plants to generate the proteins expressed in the genes. Transgenic plants are the result of transformation, whereas transformation is the act of converting plants. The edible vaccination promotes mucosal immunity. Dendritic cells in the gut can assist native T cells activate and differentiate into follicular T-helpers (Tfh). T and B cells will respond precisely to a reliable, digestible immunization. Potato, tomato, banana, carrots, tobacco, papaya, algae, and a variety of other plants are utilised as alternative agents for standard vaccinations. Malaria, cholera, hepatitis, rabies, measles, rotavirus, diarrhoea cancer treatments and treatment of covid-19 are among the illnesses for which plant-based vaccines have been created. It takes time and dedication to develop and sell edible vaccinations. Many edible vaccines for animal and human ailments have been developed and have gone through various levels of clinical testing. The importance of plant-based vaccinations is emphasized in this article.
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Originally, the 17th Symposium on Insect-Plant Relationships (SIP-17) was scheduled to take place in Leiden, The Netherlands, in July 2020. However, due to the COVID-19 pandemic, the symposium was postponed to July 2021 and held in an exclusively online format. This exceptional edition has resulted in four strong contributions to the journal. It is with great pleasure that we now present a themed issue including the proceedings of SIP-17, supplemented with eight regular articles within the subject of insect-plant relationships.
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In this paper, we analyze the effects of the COVID-19 pandemic and the preventive and compulsory social isolation, called ASPO in Argentina (Decree 297/2020), on the temporary and cyclical mobility of agricultural workers towards different productive areas of the country. On the one hand, we observe the effects on workers of Salta province who were involved in harvesting and packing tasks in the viniculture sector in Mendoza and the fruit growing sector in Rio Negro when the ASPO was declared by the government. On the other hand, we inquiry about the impact on Bolivian workers that were doing different works in tobacco and horticulture farms in Salta province at the beginning of the pandemic and the isolation measures. Moreover, we observe some effects on Bolivian people that were permanently (residents) or temporarily in Salta at the time when the ASPO and the closing of the border between Argentina and Bolivia began. The findings are based on interviews to agricultural workers, leaders of social organizations both from Bolivia and Salta origin, and civil servants of the Bolivian consulate in Salta carried out during 2020 and 2021. We incorporate in our analysis the collection of national and provincial news articles, web portals, decrees and official resolutions. We also include the findings of our previous research conducted before the pandemic about Bolivian mobility associated to tobacco and horticulture labor market in Salta province.
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Purpose: This study focuses on accessing the impact of lockdown implemented to curb the pandemic of coronavirus disease 2019 (COVID-19) on prices of potato and onion crops using the time series analysis techniques. Design/methodology/approach: The present study uses secondary price series data for both crops. Along with the study of percent increase or decrease, the time series analysis techniques of autoregressive integrated moving average (ARIMA) and generalized autoregressive conditional heteroskedasticity (GARCH), as well as machine learning;neural network autoregressive (NNAR) models were used to model the prices. For the purpose of comparison, the data from past years were taken as the period of normalcy. The behaviour of the forecasts for the normal periods and during the pandemic based on respective datasets was compared. Findings: The results show that there was an unprecedented rise in prices during the months of lockdown. It could be attributed to the decline in arrivals due to several reasons like issues with transportation and labour availability. Also, towards the end of lockdown (May 2020), the prices seemed to decrease. Such a drop could be attributed to the relaxations in lockdown and reduced demand. The study also discusses that how some unique approaches like e-marketing, localized resource development for attaining self-sufficiency and developing transport chain, especially, for agriculture could help in such a situation of emergency. Research limitations/implications: A more extensive study could be conducted to mark the factors specifically that caused the increase in price. Originality/value: The study clearly marks that the prices of the crops increased more than expectations using time series methods. Also, it surveys the prevailing situation through available resources to link up the reasons behind it.
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Onions, potatoes, and tomatoes constitute an important component of the Indian diet. The COVID-19 pandemic in 2020 forced the government to impose a lockdown from 25 March to 31 May. This paper uses granular data to assess the impact of the lockdown on the daily arrivals and wholesale prices of these commodities at three metropolitan markets. The impact was significant and negative on the quantity traded, and positive on prices, but the heterogeneity across commodities and markets was considerable.
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Poor market integration affects market liberalization and handling of shocks such as covid-19. This study, therefore, investigates the market integration of tomato and its determinants in Nigeria. Johansen co-integration techniques, autoregressive distributed lag, the error correction model, bootstrapping regression and granger causality test were used to achieve the objectives of the study. The results revealed that most tomato markets in Nigeria were not integrated. This shows that tomato prices in most markets in different regions of Nigeria were not well integrated which could affect the transmission of price. From the Granger causality test results, ten tomato producing states Granger caused the demanding states, while only two demanding states granger caused the producing states. The adjustment term (-0.849924) shows that the reversion to long-run equilibrium is at an adjustment speed of 84.9924%. Distance, population and self-sufficiency had a negative influence on tomato market integration while the telephone had a positive influence on tomato market integration. Thus, the distance between two markets, population and self-sufficiency inhibits the flow and transmission of price information among tomato markets across the country which, in turn, lower market integration. The presence of telephone in Nigerian markets enhanced the flow of price information from one market to others and consequently increase market integration. These findings call for upgrading and investing in infrastructure, such as roads, and regulating information and telephone services by the government.
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This study was conducted to evaluate the effect of HYSSOP (composed of Hyssopus officinalis L., Echium amoenum Fisch & C. A. Mey and Glycyrrhiza glabra L.) and POLIUM (contained Teucrium polium L., Cuscuta epithymum Murr and Cichorium intybus L.) combined distilled herbal medicines compared to placebo in the prevention of COVID-19. This is a double-blind parallel placebo-controlled field trial conducted on 751 asymptomatic individuals whose one of the family members recently had a positive RT-PCR test for COVID-19. They were divided into three groups including POLIUM, HYSSOP and placebo using random blocks with a 1:1:1 allocation ratio. Participants received daily 5 cc (under 12 years) or 10 cc (over 12 years) of allocated oral medications for 20 days. The primary outcome was the frequency of positive RT-PCR test among participants who became symptomatic. The mean age of participants was 36.6. Nineteen participants get infected by COVID-19 during the intervention;fifteen of them belonged to the placebo and four to the POLIUM group. Fisher's exact test indicated significant differences between HYSSOP and placebo (p<0.001) as well as POLIUM and placebo (p=0.009) groups in terms of COVID-19 confirmed by PCR tests. Cox regression model adjusted for confounders illustrated that the hazard of getting infection by COVID-19 in POLIUM and HYSSOP groups decreased by 66% (OR (95% CI): 0.34 (0.12 to 0.94);p=0.038) and 93% (OR (95% CI): 0.07 (0.01to 0.56);p=0.012) respectively, compared to placebo. Oral administration of HYSSOP and POLIUM with the other supportive health care could decrease the risk of getting COVID-19.
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The entire world is entrapped by the contagious, lethal infectious Corona disease, brought about by the extreme intense respiratory syndrome corona virus 2 (SARS-CoV-2). The second wave of the Covid-19 pandemic has been more devastating than the first. The arrival of corona virus vaccines has meant good news for resuming a normal life. However, there are some cases that have been reported that the persons who have been vaccinated still test positive for COVID-19. Unlike the first wave (in 2020), the younger population is getting infection by a corona virus, especially those with comorbidities are at high risk. Evidence from the first wave of data on the mortality rate also suggests that people with weak immune systems, e.g., older people, children, and those with underlying medical issues, are more likely to be affected by Covid-19 disease. Therefore, by improving the human body's immunity, the risk of SARS-CoV-2 infections can be reduced. In this regard, medicinal plants can play an effective role in improving the body's immunity. Thus, in this paper, attempts are made to compile and discuss the use of various plants to boost immunity and also for the prevention of many respiratory diseases having symptoms and signs similar to Corona disease.
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World trade in agricultural products, tends to increase. Turkey is among the countries in foreign trade advantages with its agricultural potential. As one of the most important tomato producer countries, monitoring of developments in the world tomatoes trade is extremely important for Turkey. The aim of this study was to evaluate Turkey's position in world tomato trade. The developments of tomato foreign trade between Turkey and importer countries were analysed using Trade Intensity Analysis Method. Turkey supplied %75 of total tomato exports to Russia. Ukraine, Saudi Arabia, Iraq, Syria and Israel are important markets for tomato export. The epidemic (Covid-19 virus) has also been reflected in the international trade balances in tomato production. Giving importance to Turkey's political relations and to boost its exports by providing market diversity, it is important for the sustainability of tomato exports. In this context, market researches should be conducted specially to find and entrance into new markets. Besides the fresh tomato, the activities for the export of tomato paste and canned tomato should be implemented.
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COVID-19 is a public health emergency of international concern. The outbreak of the disease began as pneumonia of unknown etiology in Wuhan, China. It is a virus induced respiratory illness caused by SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2). Close genetic similarity with the bat SARS- like coronavirus RaTG13 and the presence of high degree of similarity between ACE-2 receptors among various animals and humans indicate its likely origin from bats. Person to person contact was also identified. There is no clear evidence of vertical transmission of the virus yet, though its presence is detected in semen of affected individuals. Symptoms appear 2 to 14 days post- exposure and include dyspnoea, coughing, sore throat, fever, repeated shaking with chills, myalgia and anosmia. In some cases, diarrhoea, cutaneous manifestations such as chilblain-like foot lesions have also been reported. Coagulopathy is most probably a consequence of massive inflammatory response and may contribute to the occurrence of thrombosis. The severity of the disease ranges from very mild to severe depending upon the age, immune status and presence of comorbidities. In severe disease, elevated serum levels of proinflammatory cytokines like Interleukin-1, Interleukin-6, Interleukin-12, Interferon-gamma and TGF- beta along with increased level of chemokines are observed. Histopathological examination revealed pulmonary edema along with formation of hyaline membrane and monocytosis. Liver biopsy revealed moderate microvesicular steatosis. Blood examination showed decreased number of CD4 and CD8 cells. Animal trials have shown that ferrets and cats are susceptible to the disease while dogs, ducks, pigs and chickens are not. The results of Thin slice Computed Tomography showed multifocal ground glass opacities. Treatment is not specific. Hydroxychloroquine led to the reduction of viral load. On 1st May, 2020, FDA agreed for Emergency Usage Authorization for the use of Remdesivir as it showed promising results in cell culture, animal models as well as in human trials by decreasing the mortality. Maintenance of hand hygiene and proper cough hygiene is essential. Cowpathy is known to have multiple health restoring properties for boosting immunity and bioenhancer activity, which can also be utilized for prevention and control of coronavirus spread in population. AYUSH ministry of India has reported the beneficial effects of Sanshamani vati, ayurvedic concoction and homeopathic medicine Arsenicum album and initiated the clinical trial studies on Ashwagandha, Pipali, Yashtimadhu, Guduchi and Ayush-64 combination of herbs. Therefore, preventive and control measures are a must to minimize health losses and decrease the burden on health care system.